This podcast is the first in a three-part series on inborn errors of metabolism. This podcast develops a general approach to inborn errors of metabolism, reviewing basic epidemiology, presentations, and initial investigations and management.Please go to www.pedscases.com for the script for this podcast. This episode was written by Dr. Dustin Jacobson, a 2nd year pediatrics resident from the University of Toronto and Dr. Jonathan Kronick, a staff physician in the division of clinical and metabolic genetics at the University of Toronto.  These podcasts are designed to give medical students an overview of key topics in pediatrics.  The audio versions are accessible on iTunes.  You can find more great pediatrics content at www.pedscases.com.   Related Content: Podcast: Inborn Errors of Metabolism Part 2 and Part 3 Case: Inborn Errors of Metabolism Case Questions