When it comes to treating skin disease, we know that Staphylococcus pseudintermedius is a common cause of canine pyoderma. Previous dermatology studies have found that dogs with superficial or deep bacterial pyoderma respond well to clindamycin administration, with success rates of approximately 71-100%. As a result, dermatologists often recommend using clindamycin hydrochloride as an antibiotic for systemic therapy to treat canine pyoderma, with a dosage ranging is 5.5-11 mg/kg once a day to twice a day. In this VetGirl podcast, we discuss whether or not you can use clindamycin at 11mg/kg once-aday versus 5.5 mg/kg twice-a-day when it comes to dosing in dogs.