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    The Construction of Analogy-Based Research Programs: The Lock-and-Key Analogy in 20th Century Biochemistry
    The Construction of Analogy-Based Research Programs: The Lock-and-Key Analogy in 20th Century Biochemistry
    The Construction of Analogy-Based Research Programs: The Lock-and-Key Analogy in 20th Century Biochemistry
    Ebook215 pages4 hours

    The Construction of Analogy-Based Research Programs: The Lock-and-Key Analogy in 20th Century Biochemistry

    By Rebecca Mertens

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    About this ebook

    When the German chemist Emil Fischer presented his lock-and-key hypothesis in 1899, his analogy to describe the molecular relationship between enzymes and substrates quickly gained vast influence and provided future generations of scientists with a tool to investigate the relation between chemical structure and biological specificity.
    Rebecca Mertens explains the appeal of the lock-and-key analogy by its role in model building and in the construction of long-term, cross-generational research programs. She argues that a crucial feature of these research programs, namely ascertaining the continuity of core ideas and concepts, is provided by a certain way of analogy-based modelling.
    LanguageEnglish
    Publishertranscript Verlag
    Release dateApr 30, 2019
    ISBN9783839444429
    The Construction of Analogy-Based Research Programs: The Lock-and-Key Analogy in 20th Century Biochemistry

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