Discover millions of ebooks, audiobooks, and so much more with a free trial

Only $11.99/month after trial. Cancel anytime.

Microneedles for Drug and Vaccine Delivery and Patient Monitoring
Microneedles for Drug and Vaccine Delivery and Patient Monitoring
Microneedles for Drug and Vaccine Delivery and Patient Monitoring
Ebook784 pages9 hours

Microneedles for Drug and Vaccine Delivery and Patient Monitoring

Rating: 0 out of 5 stars

()

Read preview

About this ebook

Provides comprehensive coverage of microneedles for delivering and monitoring patient drugs and vaccines

Microneedles are an incredibly active research area and have the potential to revolutionize the way many medicines and vaccines are delivered. This comprehensive research book covers the major aspects relating to the use of microneedle arrays in enhancing both transdermal and intradermal drug delivery and provides a sound background to the use of microneedle arrays in enhanced delivery applications.

Beginning with a history of the field and the various methods employed to produce microneedles from different materials, Microneedles for Drug and Vaccine Delivery and Patient Monitoring discusses the penetration of the stratum corneum by microneedles and the importance of application method and force and microneedle geometry (height, shape, inter-needle spacing). Transdermal and intradermal delivery research using microneedles is comprehensively and critically reviewed, focusing on the outcomes of in vivo animal and human studies. The book describes the important topics of safety and patient acceptability studies carried out to date. It also covers in detail the growing area for microneedle use in the monitoring of interstitial fluid contents. Finally, it reviews translational and regulatory developments in the microneedles field and describes the work ongoing in industry.

  • The only book currently available on microneedles
  • Filled with tables, graphs, and black and white images (photographs, micrographs)
  • Authored by four experts in pharmaceutics

Microneedles for Drug and Vaccine Delivery and Patient Monitoring is an ideal source for researchers in industry and academia working on drug delivery and transdermal delivery in particular, as well as for advanced students in pharmacy and pharmaceutical sciences.

LanguageEnglish
PublisherWiley
Release dateJun 4, 2018
ISBN9781119305170
Microneedles for Drug and Vaccine Delivery and Patient Monitoring

Related to Microneedles for Drug and Vaccine Delivery and Patient Monitoring

Related ebooks

Chemistry For You

View More

Related articles

Reviews for Microneedles for Drug and Vaccine Delivery and Patient Monitoring

Rating: 0 out of 5 stars
0 ratings

0 ratings0 reviews

What did you think?

Tap to rate

Review must be at least 10 words

    Book preview

    Microneedles for Drug and Vaccine Delivery and Patient Monitoring - Ryan F. Donnelly

    Hdbook_preview_excerpt.htmlK$ו&WlT̈|@2)de3S%\_w7\vv TUYJ׏/}ܗG$1 J<_nr|wrŗ_~o_}غ]rؗrl}9VbW7n,jVXMSwmQգ˧b}=w+nўP++i(+쇋MrnQ^Z,Aa9ˋU?m_a[ʟݚôƲ܀qNrM#}-\Om5xbEqec0DUu}SؖuhӖ-I'o壿?]>-3nyd]z&*iWT]:/?E[wMKWb,o\[L{|tݪuM, +92os 0nWWEU(;'e_$n޿9M.l)؜^HC3B}ۻ0+W|RU Jٷ֍B7/i-e-G eVE9 ]U8-@rF&4,0buيRWPur턧Ӆ,q/p8Y ]/I1?[_ޖu Xcj'm˥KW SLT65;7M:`_M[9re4neQfo8tRS?cq-v!B)vZV= q)m0O_-_~W^](:_doʞ߁: \oߔm=@Zf dSyp=gQwXݢX W5NvB"B]C6ǡߺ90ծFC`^Dn]q:DS4ba/eN#t dK)k!䐰]_U?.2K/x~D|ǜ3<ȷ]#vy w²Hrܪi4N69^SVDk5N3ZD$}+6[Ib5H~-ކ0Y<Ш ѣUy{r?MxiZe'z8w}/|HBo[!oi#&R^t} zb}\r~:J0zݹQԅ@j E? U 4kzRZލWȪeHJwJT%e٤rGatKЈ@Z eX XQ6 Fj(gǟod=@ȉQd37-zu 5Gլc{0v$-2;<ɢ7dgPĂ[I 1,K/EdX}{sԵBݲ A)lALb^nй'ZNʌ(VɁ0]rhyiO˕;tj"Cik`B$(?tAMD{ន-M"@SK4go;/Ξ1zxFdEm,=^Hyg/ro˞~rJϻ(QkhT$}D':PAyUFFl^&@|+XW@F1VZJ;F/ 龫7A`N@CNҌXe H`]75+~cM$3lQ)0EkDP=h]@J"; pmx&#ˈg,SڼL lXlѣOjNL\hEvp.7g2T^LAGj=B_1\i)¹եr̎Q|"Z!99%/FAqKcaWӜz7(SOu 6]"CjMi]1 mGX({WgФ#90 [bMH7baӼnfqA$s:f !WWJ /X#i-l=\r1tAQNGw*SVu*gԦk';v7tv(6rB2`L)xۻijEfaAkUz{0]8FM-(59h}S*?YvX8j _\1fqXwr64@]53;(P9 [ѦsT5\BduG(+2`Y'3JoFP)f3I[P;4a1%RɑkuЄ+ҳǫ` iuht 5P})dnm]C~]O@rdS>5* q5  vCT^jhN~T\#`17mZ<(V\lxzEGF{edg9R&)#%7eXlSɫ̤C0nX(؍Xou7 lB{bZsƯԁI7& JoUXM0=dmrHL+': 3="΅6:3X.irQq;/\oZ #XFh;Zt 4 s7VhL,~MЖG\~٩,0OӇVkg;]Vlh2ycV/c%Kj}W4Ͼ\~ހ.s7mgglA v_lyO?:bG!z=`92d|1Sd.Om(0sdF$lytɊFm4={Q-o @a†w>G7knE%WiT%j=J)cWިZ( rHE3Dy!#ͭdMSf *B\֣!<3q\!qyMC;P1IcT5Nz52dWdAoNP䎋tl#ĂݵX]}p}.c7]G/X_~ƕ'W8w9g_O[RrM&d7,Z$_4#cz4@vT<7%bѭ.M+o6%,[aPj̩o0fp@ަ㘉nE0kL t֤/ˀp"8Β<9[`eT/!7lz ˖_sDdԩ ń`ɿր Kw?4{}QiEBG/\ "(.+8gQFߟ#zZmcwj;sT|;mYBZ1ay~h6c< +sBfBLFa1:;E+_ KXZ&nqH!O ^"^zj~k+xgL}W fwwj\es:zvq8Y8b^8i&3¶njL!usUTH{)J̞;41 :B>}ëWŋBRwNO'931,:zUJ hDA.VKȂoewn9ik&$Ǽt?u 1g1J ^?tSz||5ۡ90ֵ[U!2SUHE{~(CCBj8i,[V3X]-w]&nR$$Ss#'#bid;r>XV`C.+GCf!Cf}a(J[jNw͞ U(Yp);pCcbSW,:۰^@W/~Ni޲u>*!-Wim}0>4WSOJBNG&'l,4S(cFEp,!*É(Z|TU L F.42 IFI*K/^F9 wiNTMIjT)ڨA֌iTJoE 'u*G)bD6)6;1P֞s Ro[Ũ35Uj(cIwz= P΢mQ>CZ)_mjZjC=tmTZh \ngΙ$J`*JM@!Ls= R TeFWRI|yqYNj^؋JP*NVx_DžZOLeJAa ^=0qXЏҿ=-ڮ [Ms9 tB PB"JOxHKY!τ\bϟ>Yօ%D McRE&w!ܓ\ҺzC2Wpџ2hyMY/Vb]sAUhuqWr)M`9XGgzV(~ PC_ɰmf{x|A_Xf-4U{GbgGS|HQaf 4:_1A]9Nv>ڇ?;OKeiY͎gF&¨s3y vf ;WmKME!ȍ1ɑxgڍΙƂKFX*-K iUsŽ"۝rY׼:Md%}D#P֛f?K{ڈ;Gd` iז+2;ƌޚ,+o: ;9jm3X#,72FT"-KT1y|i *H}T-H' ?d@1q׈{sC%nhҜ%jGʕFP`H5Hf)L^s0*B%@aѴXc8),pTU݉UCmk +J_ġZd 8jNpDC5RHi;zgn"(9Js,օl2AIb:80$HfA]*E}=+c[<3ׁNU&9ZXV  xlXU3C{feR7 N`2(| |B@b6|yv /!;)AM+7 deb膂~+τ|nsFNmDAtZ&ώ^Wh2&I,}ڶt#)xjuɻƩ2}Y/n#JB! L !Î,6N!Gc}T& Y[6;14]8nLz1;術)q6Y'^݇#!A4רتB-rܺxRlPs!ϒ>$PCN4=Ӱ]Sb$:ƴy@pIqڸTc.졣ekb%QeM7XcgF[Mݮ)ýd"ӤQ}K RX00yLw"segO Ί Cʶc壐\;DZcEu!XV7ZLDVZ&b2$orR`wZXΈNL-ba|B91 F!"|W^- u+CX1?GtI|A,M|(.p+ad+RmS\D׮W!xbNϗI5>:i?ճP5Go-M{}֒aߺϞs`j,!ha͸=/B!l'`MZ6,>yS-Fd6wj74*h[ SvP?-ԥ0mDe2$r2@ϥ?l`cg iLf e|Mb`he@U!용A |z#̭^C 18i$B7es\ai9곇F[ _&x=},_=7-Ar(V޳@x*$=|im-X5?h-/3RGlߴqݰ|c;*Qz9j_Ѫj,s6mFnE_uqm٬󐝞"cvח~]*5:>gH30O mz`gY$<ߺd0+`M ۫Rj%RH@2PTO7 [l3x$ Py=[R$JFJ-Ba g.&.=$ '.B{"Em$=ɔ )nS.֖y6>h] ~bJtErfVK/?u -ڰ&uA_ಆz feaiQc{`Ϭ bn|C)'C Ÿu3аC JP彝5l֖y5HCVՖ& }aWƘحlCqelh.;pkN|\!h4Ep6VMےDd/ ~ Fhگ}v5Eh=i܃q|Qe:8lGr &Uz vd8>+k\عSA r>+bƋI297)x!SIs0Kr~.$rk:0R.H8h$|x_,Gzf(.qBT]}F߽6!b2b}vS.!1~|VlR<9N=nEUiOe܎aK}^oCW>eO96TLB>M7~`L`' deA=!r2>gf32>(AL&wXplgx u%9 H^zlfL0|ǐUt̼c/uH@/?S-\pSI/<2+rVWZ(ýKsY"&iYj]oYhO~2k1g$IVݺF mpwhC>>$f"d6eXMdyeJ1sY10x mO*1 T[./Vb#cPPc;K^oIZc+Dd&Z?;f] [h=7"o/7 dYfs'^7p!P $u+no'owK| Sx6lC]n.DQI=|}&w^f+ P5Y(Qw&8VI :`hSk~ FjDWECYuw mNIveaHf] ےo zǩiZAij4˧my0/=~@a-`J((Բ*7^ .cAqQ^ݥ>Tg>LNcc: `26ywiWJ˳`b0H,1iXca oo5 wTwsm6CsK;3#ZL<+3Qz9Ս5$ x.Jo8̓ [b-K|X{s Y[ 8UeMiW %{Zn;6uՍl3g"GƟǼZh$ʦ} 5] q-,X/ nsUnj^2PspkɁGGF MvOG6V;hH{[(Kf87mZzJ|CW*M~`Ef`Xirr?jJzٹv_xB PnD_P"1d_xA5!ͺ>M=G!h}G!C) c $by>WWF gާV.!YCw\vj /Th9QUwLz2kbaF:!fih8> 5OPLɒO۟upe}yc"v J[mH;$[.烖)FHkj,=YbGPL{oVQf^Űv.t*{bn-:`@$ŋ;yO-&Ѯ9>]}bRoL׷e^ݡie\l[v=2;yĉIm2 R͔K=9Rzkx#RS`9Ob 럘Þk2c@riB~۹y؁qvdPz^{(`kkV&X2 D6!WLwm=]@KNI7dZd?6^t?]?gmOuBL%⻿eeb~wбlSؽ'ӝxe2:r=qh;L&r^.W?ϯAxbԁ/芓3(#pcd,Bq{LLK?Zh^Ȭ^RH˪B'u/%AKe#$>\~PS۰ }֒np2_&Sz$jE>Zp]XQãcl)0}p\_@m 8q(/v2<43n39SDwmcIvyi|I+o p]T${73Zep갢oxoߋ6dٔRaދTp}v/ٟ ޟ+%J"x"SH8%YAßobO.)sjf+4@[zW:=|2gEW"DEN䱚ޮWw%o 7x$"½9d* όlk$ $Ja7@!_߮KԵs,F_;}N.۳8#i̺7MvK@^8!U| : "aNwAخ3{,R69hz2vݎ}bVNGjOP[5TB;jOHJz8mI.g|l[[N'A{EB,+AMz(+|чoB->^i?-!1tYޑp+EݙUw}Ȏ*kRƤݮcr[]BJx"tǘĨ9- @ŠyۙT¢e[hZ#u^[6x#Ko|QWo9Spvtc#Hݴq :@D͠| ڴiO4PW bk]\2?⇸EVs"xjNXUHB@=ɫ ਴e&S3ǃ p9H,-\|30vY#lg"6*!J|'n.Γk2\7j4͘ȜXB2;d*Fu}g-(whG?F#>~57H5~]Zyw]vr<[pȯ&O?/dv(gp1D%!pC&6?wU${]?} rY(Yz ZbEJkxeM ^O+w$G7+~1wߖ{Ŕ]C yj3/gQg@X$dKGe˹PQliy7<CH[8NjQuhڐg]fyaXS%'(ǖ4]hy x7Q){\Zxѥ^׬4ݗ"Rح59Ǘn|}K?˓]< Hn{96A[ƴ4-Wpc͘Rf3$'W!4\MX*\b rZVS§]-ͦqrȇUV+U8i%ʜm 6~pBؗ[j#) E8էnĄli CSErBa'J:3Sf+:j&N]Z]MxiZ<X/F,2|R'e-ZgqabǃWR󐶒ݡ[5Ou]/bFy_n4w۰OӑCGv wRK 'm-:)|g5Gqߣk[.fs0>Ƌ&1"cnk 2G -̪Ьb|rj# iA>tQo~)nc9>Fق>[d$>>{ÍUГb y([WԹJx-'q?ʱ$Y2M|<.\sy֊Fn*d W\?}t@EfhdAEr"Wv~{&,x7 tҞ|_<瞦|51"c`-Qr$r<-rZvЊM*d"]SN '?Sgk{UP!Kg{+Ziȣ f6w@VZAzh/@̀~=LuL.JBw2I.` /!xt#yjV0- |-`%Z"sV̖-Ff&,Z4KAyZ/ddΣ!w2M,`ԁ;g)c$S|Y6FyN5*=zT*ͥOqT5$[O9KiXKq0vC'gWOW`b?}&b!=xݹSsY5Olg' J/5or]x lsy^"*$˛UXaV¤!TO[\ 'H?Aߓ:-cTuzpk8ܴ+լl(bOQ0w4vv Nl1üFf \8>Sh}y]543vj꠬5_^iXIs!Kq9f_YO惌KC%١/lJfeVg4{O_EyzcYu'ӪwK˓,Ex1{D|e.#NA6yAw4pMґVEpx7NH2j ϝob?3RV7~ B,@~5o.pLMT c2osnR nkDAE'1'm@`5[π>n?{!#UpCu{$ƍ<jyτ]9_6n|~4=zڠh gTj1 1ro^yԪAKw  wաd</ٷw´86<%;#)fu9v5+edx_nD1֪%w-2I= S<32\3Ka Q 8W"/]G37VYAҍ;,S/񾲊&=%v>X2J<+Le#/^ֽNUN:sqX 78Zx]i.u`X <FxH4L\ |v3Klk1}Wk3d횷|"K&Vy\0S@ܳGV#/fH/5݊Mڴ] e\ISލ 05't-o<-F~_mwh b݇Pp>?飰QAh?I\PL5ƵTpj]kI?ezpNWJp|]p)39q\7H;*rѓخ7ȞY$4 nSչgݻamQ{%K>,5C"r,STf3in1|_N34$U鐋Ls:VF-"/WÿP,"^H4rW䰩]}r ogdn[axnʐ%z>V~nT> /gDZ# #-""a|W&gv=[B$Z^z3y$15\њ!V_5MLk7>Y~E#7 E5g3f# (9^a4k"5lA%'$Qa$ʀUd^ʼnDXsny3 兛L+W39Y,WhKCVsHzDY!z}/KVڅ%WqA=rGpN]`clbS(ԩݡ!\]qcwڃbF10jwbXElms^v:8a}3g ޫ*w?xtj;mm}, hP31rB1|O%8O~,O=Ȕ>sm}p OxY]78S: Ag -ξEn B"|O{QR3̓a̹c!kx=Dsݘ|7X0tT2mSkA U61gXI >٤}o a5/E`Wҍڭ$mm#
    Enjoying the preview?
    Page 1 of 1