Stem Cells: A Short Course
By Rob Burgess
()
About this ebook
Stem Cells: A Short Course is a comprehensive text for students delving into the rapidly evolving discipline of stem cell research. Comprised of eight chapters, the text addresses all of the major facets and disciplines related to stem cell biology and research. A brief history of stem cell research serves as an introduction, followed by coverage of stem cell fundamentals; chapters then explore embryonic and fetal amniotic stem cells, adult stem cells, nuclear reprogramming, and cancer stem cells. The book concludes with chapters on stem cell applications, including the role of stem cells in drug discovery and therapeutic applications in spinal cord injury, brain damage, neurological and autoimmune disorders, among others.
Written by a leader in the field, Stem Cells: A Short Course appeals to both students and instructors alike, appealing to academic enthusiasm for stem cell research and applications.Related to Stem Cells
Related ebooks
Applications of Flow Cytometry in Stem Cell Research and Tissue Regeneration Rating: 0 out of 5 stars0 ratingsVeterinary Embryology Rating: 0 out of 5 stars0 ratingsCell Culture and Its Application Rating: 0 out of 5 stars0 ratingsNecropsy Guide for Dogs, Cats, and Small Mammals Rating: 4 out of 5 stars4/5Avian Immunology Rating: 5 out of 5 stars5/5Cellular and Animal Models in Human Genomics Research Rating: 0 out of 5 stars0 ratingsThe Evolution of Molecular Biology: The Search for the Secrets of Life Rating: 0 out of 5 stars0 ratingsColor Atlas of Veterinary Histology Rating: 0 out of 5 stars0 ratingsHuman Stem Cell Technology and Biology: A Research Guide and Laboratory Manual Rating: 0 out of 5 stars0 ratingsCell Culture for Biochemists Rating: 0 out of 5 stars0 ratingsKaufman’s Atlas of Mouse Development Supplement: With Coronal Sections Rating: 0 out of 5 stars0 ratingsThe Science of Stem Cells Rating: 0 out of 5 stars0 ratingsStem-Cell Nanoengineering Rating: 0 out of 5 stars0 ratingsPrinciples of Stem Cell Biology and Cancer: Future Applications and Therapeutics Rating: 0 out of 5 stars0 ratingsPathology of Domestic Animals Rating: 0 out of 5 stars0 ratingsThe Reproduction of Vertebrates Rating: 0 out of 5 stars0 ratingsControl of Pig Reproduction Rating: 0 out of 5 stars0 ratingsGenetics of Reproduction in Sheep Rating: 0 out of 5 stars0 ratingsExotic Animal Hematology and Cytology Rating: 0 out of 5 stars0 ratingsAntigens, Lymphoid Cells and the Immune Response Rating: 0 out of 5 stars0 ratingsResearch Surgery and Care of the Research Animal: Surgical Approaches to the Organ Systems Rating: 0 out of 5 stars0 ratingsBluetongue Rating: 0 out of 5 stars0 ratingsMarek's Disease: An Evolving Problem Rating: 5 out of 5 stars5/5Retrovirus-Cell Interactions Rating: 0 out of 5 stars0 ratingsDevelopmental and Cellular Skeletal Biology Rating: 0 out of 5 stars0 ratingsNeuroendocrinology: Volume I Rating: 0 out of 5 stars0 ratingsThe Cell Cycle: Gene-Enzyme Interactions Rating: 0 out of 5 stars0 ratingsReproductive Pathology of Domestic Mammals Rating: 4 out of 5 stars4/5Clinical Atlas of Canine and Feline Ophthalmic Disease Rating: 0 out of 5 stars0 ratingsSmall Animal Fluid Therapy Rating: 0 out of 5 stars0 ratings
Biology For You
Anatomy and Physiology For Dummies Rating: 4 out of 5 stars4/5Anatomy 101: From Muscles and Bones to Organs and Systems, Your Guide to How the Human Body Works Rating: 4 out of 5 stars4/5The Seven Sins of Memory: How the Mind Forgets and Remembers Rating: 4 out of 5 stars4/5Ultralearning: Master Hard Skills, Outsmart the Competition, and Accelerate Your Career Rating: 4 out of 5 stars4/5How Emotions Are Made: The Secret Life of the Brain Rating: 4 out of 5 stars4/5Why We Sleep: Unlocking the Power of Sleep and Dreams Rating: 4 out of 5 stars4/5Sapiens: A Brief History of Humankind Rating: 4 out of 5 stars4/5The Rise and Fall of the Dinosaurs: A New History of a Lost World Rating: 4 out of 5 stars4/5Dopamine Detox: Biohacking Your Way To Better Focus, Greater Happiness, and Peak Performance Rating: 3 out of 5 stars3/5The Obesity Code: the bestselling guide to unlocking the secrets of weight loss Rating: 4 out of 5 stars4/5Gut: The Inside Story of Our Body's Most Underrated Organ (Revised Edition) Rating: 4 out of 5 stars4/5Peptide Protocols: Volume One Rating: 4 out of 5 stars4/5Homo Deus: A Brief History of Tomorrow Rating: 4 out of 5 stars4/5This Will Make You Smarter: 150 New Scientific Concepts to Improve Your Thinking Rating: 4 out of 5 stars4/5The Grieving Brain: The Surprising Science of How We Learn from Love and Loss Rating: 4 out of 5 stars4/5Mother of God: An Extraordinary Journey into the Uncharted Tributaries of the Western Amazon Rating: 4 out of 5 stars4/5All That Remains: A Renowned Forensic Scientist on Death, Mortality, and Solving Crimes Rating: 4 out of 5 stars4/5The Winner Effect: The Neuroscience of Success and Failure Rating: 5 out of 5 stars5/5The Code Breaker: Jennifer Doudna, Gene Editing, and the Future of the Human Race Rating: 4 out of 5 stars4/5The Soul of an Octopus: A Surprising Exploration into the Wonder of Consciousness Rating: 4 out of 5 stars4/5Lifespan: Why We Age—and Why We Don't Have To Rating: 4 out of 5 stars4/5Lies My Gov't Told Me: And the Better Future Coming Rating: 4 out of 5 stars4/5Suicidal: Why We Kill Ourselves Rating: 4 out of 5 stars4/5Jaws: The Story of a Hidden Epidemic Rating: 4 out of 5 stars4/5The Blood of Emmett Till Rating: 4 out of 5 stars4/5A Letter to Liberals: Censorship and COVID: An Attack on Science and American Ideals Rating: 3 out of 5 stars3/5Woman: An Intimate Geography Rating: 4 out of 5 stars4/5Other Minds: The Octopus, the Sea, and the Deep Origins of Consciousness Rating: 4 out of 5 stars4/5The Sixth Extinction: An Unnatural History Rating: 4 out of 5 stars4/5
Reviews for Stem Cells
0 ratings0 reviews
Book preview
Stem Cells - Rob Burgess
PREFACE TO THE PROFESSOR
My justification for writing this book comes from a thorough review of the scientific literature currently published in the area of stem cell research. While an enormous body of knowledge exists in this field, there has yet to be a comprehensive college-level textbook that thoroughly and properly addresses the material in a manner that allows for the student to grasp, retain, and get excited about the discipline. Many works highlight unique or ground-breaking findings or delve into the broader concept of stem cell identity, function, and usefulness to man, yet they do not address the field with the all-inclusive effort needed to give the student a strong understanding of the need for stem cell research. Second, most literary works in the area of stem cell research gloss over or fail to drive home key specific findings, definitions, concepts, and details that are required to give the student a thorough understanding of stem cells and their impact on therapeutics and medicine. Third, when key stem cell research and discoveries are described in teaching materials, the researchers involved are often not mentioned or given the proper credit for their findings. Thus, I have compiled a breakdown of stem cell research that highlights the history behind the discipline, emergent groundbreaking findings such as the discovery of embryonic stem cells and induced pluripotency, and given credit where credit is due. Within the body of each chapter, I have included Focus Boxes on key researchers and Case Studies highlighting seminal findings in stem cell research. For each Focus Box or Case Study, I have tried to provide an example of a true leader in the field or groundbreaking study. To ensure that the student absorbs the material at the end of each chapter, I have included a detailed summary of the text, key terms, review questions, and all cited references. The key term definitions and answers to select review questions can be found at the website www.stemcelltextbook.com. It is highly encouraged that the professors utilize the summaries, key terms, and review questions as study materials and ask students to periodically review the corresponding website for continuously updated information related to this text in particular and to the field of stem cell research in general.
The book is organized into eight chapters that gradually step from the history of stem cell research to the basic concepts behind cell culture, key stem cell-related findings, and applications of stem cells in drug discovery and therapy. Key topics I have addressed include:
The history, early studies, and the rapid advancement of the field of stem cell research
The basic requirements for a cell to be considered stem
in nature
Types of stem cells and their capacities to differentiate into various mature lineages
Breakthroughs in early stem cell-based therapeutics endeavors
The differences between embryonic and adult stem cells at the basic and translational research levels
Induced pluripotency
Implications of stem cells on diagnostics and drug screening efforts
Stem cell-based cloning and its ethical considerations
Chapter 1 begins with an overview of the first concrete contemplation of the existence of stem cells in the early 1900s, and how that hypothesis rapidly evolved into accepted theory. It transitions by slowly introducing the concept of stemness
via seminal discoveries in hematopoiesis, mouse, and human embryonic development, and even iPS technology. Optimization of cell culture conditions for various stem cell types and advances in cloning that utilizes stem cells as source material are also discussed. There is also a special section on reproductive verses. therapeutic cloning outlining the discovery of Dolly the sheep. Several examples of the use of stem cells as possible therapeutic regimens, such as for spinal cord injury repair, are also described. The chapter closes with a briefing on the limitations of stem cells in therapeutics due to immunorejection and efforts to save endangered species through iPS cell