Ebook970 pages
Cisplatin: Current Status and New Developments
Rating: 0 out of 5 stars
()
About this ebook
Cisplatin: Current Status and New Developments is a collection of papers presented at a symposium sponsored by the University of Alabama in Birmingham Comprehensive Cancer Center and the Bristol Laboratories in Syracuse, ?ew York, and held on September 27-28, 1979, in Atlanta, Georgia. The symposium provided a forum for assessing developments with regards to cisplatin as an anticancer drug, with emphasis on its clinical application in a wide variety of adult and pediatric malignancies as well as the mechanism by which the drug appears to cause tumor cell death. Comprised of 39 chapters, this book begins with a preclinical overview of cisplatin, focusing on its mechanism of action, pharmacology, antitumor activity, analogs, and toxicity. The discussion then turns to the effects of cisplatin on DNA and the possible relationships to cytotoxicity and mutagenicity in mammalian cells; lethal activity of platinum compounds in combination with pyrimidine derivatives; and ultrastructural effects of cisplatin. Subsequent chapters focus on the rationale of combination chemotherapy; toxic side effects of platinum analogs; radiopharmacokinetics of cisplatin; and the use of cisplatin for the treatment of malignancies such as ovarian cancer and advanced adenocarcinoma of the prostate. This monograph will be useful to oncologists and pharmacologists.
Related to Cisplatin
Medical For You
The Vagina Bible: The Vulva and the Vagina: Separating the Myth from the Medicine Rating: 5 out of 5 stars5/5Women With Attention Deficit Disorder: Embrace Your Differences and Transform Your Life Rating: 5 out of 5 stars5/5Mating in Captivity: Unlocking Erotic Intelligence Rating: 4 out of 5 stars4/5The Emperor of All Maladies: A Biography of Cancer Rating: 5 out of 5 stars5/5The Lost Book of Simple Herbal Remedies: Discover over 100 herbal Medicine for all kinds of Ailment Inspired By Barbara O'Neill Rating: 0 out of 5 stars0 ratingsWhat Happened to You?: Conversations on Trauma, Resilience, and Healing Rating: 4 out of 5 stars4/5Brain on Fire: My Month of Madness Rating: 4 out of 5 stars4/5Mediterranean Diet Meal Prep Cookbook: Easy And Healthy Recipes You Can Meal Prep For The Week Rating: 5 out of 5 stars5/5Gut: The Inside Story of Our Body's Most Underrated Organ (Revised Edition) Rating: 4 out of 5 stars4/5Adult ADHD: How to Succeed as a Hunter in a Farmer's World Rating: 4 out of 5 stars4/5The Diabetes Code: Prevent and Reverse Type 2 Diabetes Naturally Rating: 4 out of 5 stars4/5The Song of the Cell: An Exploration of Medicine and the New Human Rating: 4 out of 5 stars4/5ATOMIC HABITS:: How to Disagree With Your Brain so You Can Break Bad Habits and End Negative Thinking Rating: 5 out of 5 stars5/5The Art of Dying Well: A Practical Guide to a Good End of Life Rating: 4 out of 5 stars4/5The People's Hospital: Hope and Peril in American Medicine Rating: 4 out of 5 stars4/5Living Daily With Adult ADD or ADHD: 365 Tips o the Day Rating: 5 out of 5 stars5/5Herbal Healing for Women Rating: 4 out of 5 stars4/5Holistic Herbal: A Safe and Practical Guide to Making and Using Herbal Remedies Rating: 4 out of 5 stars4/5The Amazing Liver and Gallbladder Flush Rating: 5 out of 5 stars5/5Hidden Lives: True Stories from People Who Live with Mental Illness Rating: 4 out of 5 stars4/5Blind Eye: The Terrifying Story Of A Doctor Who Got Away With Rating: 4 out of 5 stars4/5Working Stiff: Two Years, 262 Bodies, and the Making of a Medical Examiner Rating: 4 out of 5 stars4/5Tight Hip Twisted Core: The Key To Unresolved Pain Rating: 4 out of 5 stars4/5Period Power: Harness Your Hormones and Get Your Cycle Working For You Rating: 4 out of 5 stars4/5"Cause Unknown": The Epidemic of Sudden Deaths in 2021 & 2022 Rating: 5 out of 5 stars5/5
Reviews for Cisplatin
Rating: 0 out of 5 stars
0 ratings
0 ratings0 reviews
Book preview
Cisplatin - Archie W. Prestayko
_ book_preview_excerpt.html |KsH_YIR4(fU(#S} }˚͜6?a}~D=" AULlYW+I~{[ii{fݢ]^di2?7q
7|ǞѼ8,8JX}WʼﺓÕ܅σ,0}P^^L`<~7p<\~0ߏۛ;V<>{~.ᅛ./;WKa|;x{q2nLO|ݻA;8}[@L&ӽ??=܌iU|<0(ޗ{q4M4>wvzDmDdo0nWnM`pat"cK8yx!nt7uǓѧ86s˨vzAwۿt/HF}+=xiwݟ|\*G7vqw#o<|0= \Yp{K@0L>y+Щ`E.y붏܅"?\kGBYj0ChMȄl,}o'4v} ;iy
g0}XYH *kP3c+J~(fTl^kt'}Oۛnr@@!6c~'ZR1oK[ ]fonold&n_-2X{Yr {1
X:x㘱'aVAumoh046||}c,nX lCu''6͂E/c_?:Q (rE*(ީ{wo =EfOieiLbsZ$zƿcoQ.<AAi(/3E4Kb~DNOBzӵW+
NDkp3M2T`M(@p0 ȗ%6*Cv\#4X _∇ \jb՟;DU-TO|i˅ ,JYN{MUÛuby9CЅ_l#͢yfjיf"{$dPDO9pzY5mu8mÏB&~ܳD~OK2!I5!e\ii id~!j)BW'd eBE&}C{]>%O>맺VF75NүQٲǾyã4 2oaf*SI679!2!nff#-rEY^x"}IH4WTesVUx~Pz{˳}үWd-5vPi~.I;r@u/5}Mk$6XGpbi$j;#K
pX[@Z=ݕh = >{ŻgȳkiNyHhh~xq iv6gnӗXPǪE{֛k -_Rr34'o=qx ,:o+/E*u$C. Dؚ~Gֲ DfהFD˥;KLc TL~O#U?^6B?[/VIWfvڟB%x *"HA<]1+5gEf//*MB~Vө&p:Cִ嬪w64X$ϵ?s/^%'2nMCoRYt_BE
IBrrK{iQk2GVXig@mGP 2G1QM-^8lU(RSYgG ]oaCiD.*7 (p(o'O~?zfU )c=k^uCn¡J!]`{V [Bv.pUQd?f"Q339Y9e+U !Eˌ&kzpO38+U &0 6K
Ƽf$5#*{cuh
Qe3&,_-p q(Z+L=GE"Ԁߥ:,/}NbihĞWOqC9a
9 ϏIFnr"j7^ bHHa+^SYGApڇdk@!42sMFDI`M_U}vAA2bX%*`?
[?)JWuv$`8>C(hRJW(ֵ+@>5gNn
if+&AI/(-^.L-ʃ,e5v%!S5w?eJ{{{HAirb:)ebI0 #>x'ʌCL`,+C.A9N#
߈bLY5I:}/|d7a ySSHu}"/(8d#y\a:vI#*|z-9UhH4\J{.M{on J`SOJ-ᨘj7
Hv!O"0c9Soi"
jhe6jA?#MfevS_Fb@a¸z_.eۯٰz<Iaˣ?Œ@JA=QP¡\WETzJ-ĵ+uHz:dwjcA)(L'(:"5O#PCD?)Ak. %d:]U9}!Vy k?_W;H:V%
ŕE PS>!)ue+zw;ҴRYP.c'MYs5FUM: brE~-EeiD&!$6vr?yͩm^tQIByDg
S$^ϗH@IabVap#0:NU(t0jVVk(5^
ky3xV'~FT, bD/plsf$[҄e#10ҕS*PVL `H|&Մ(c
D涒χM]FJC͊յrFs-:`sv}>1oy_:NlfA9'f~MF>#XOj ;#
gXڴeiëL\s>v\)SV%˜[QyVd+Xd+]%oٕl^Z#lwn1p0U^EJ)ZvOkm~8ٟC=6rmf
Zj\D_l1fiFZʹY@bP懑=[PnN "ĒT"-I'I&2-N(TzES5k]ZzjjdaÞ6و`"sb$#н*q:ယ>(H+l]Ι"C,gI%rH
^Et
Z^ƈ?j#w]T9;J=(l/,@4B-/sGIGSy-װybadžܵzM%Q,^O/ANlJ ϪV[Qh.WҨ#^\:ҏSw.ꕪU7pGM "?AC?m"wఱpCd>v% d,SɌKuh(Lo=ME-Ⴙ ܤ6p<%%iT|s>fUQblWKwNTFu']sAuÞۍb*n},%;pӥ.gP.i8Fۭa`B}]K9#m7%`S,.?4tpa"2&9D5HKwN=?8P48|(Gp#إAI WmԑU9yHc;O)F@!WQK#,۫4ƞ˹ьnь_l@JuӦJU&E¼BjDy
Zǭ4ϜluOWMg-YBF놩r=* 7d;V$7|}7[^0Tt.LbQDD,Q)W^JNmVLB$8*2p#*q66V iq Mwڠ^v%͞dS t.T4%ijA0;4 ͨ??
~V[8Ƈ$@H.O{I9C&YŤ=P"?QUsz93~wn'98:y-z&iJȄ efu|~u|rzz;f'Dx0"QlJV=9;&tc ]7W''Q~oс#*F-8M9|n8x@Umcp>aX5$p=q~
u\^OϩVy|ֶ(+ 5IgEgFVmq ݺ7Dz|
8z>6伍-'wܥsvA¾,T*:Ǖ"7n$X: ŗJ5%+xlW'>usŏ6WٺD+5o˥G9m'b+.*$kxD1!#rtY*G0l
jӧl' 6#dNYj|PJ火
^g`91}rQq!