1 NGC 5466
We start with globular cluster NGC 5466. Listed at mag. +9.2, the core of this 9-arcminute-across globular isn't as bright as it could be and its overall appearance is of an object with a low surface brightness. It's relatively easy to spot with small instruments, but that weak core means any light pollution in your sky will have a significant detrimental effect. You'll need a 200mm or larger scope to resolve any stars, a