The Atlantic

What If There’s a Secret Benefit to Getting Asian Glow?

A genetic mutation carried by about 500 million people makes drinking dramatic, but may protect against infectious diseases.
Source: The Asahi Shimbun / Getty

At every party, no matter the occasion, my drink of choice is soda water with lime. I have never, not once, been drunk—or even finished a full serving of alcohol. The single time I came close to doing so (thanks to half a serving of mulled wine), my heart rate soared, the room spun, and my face turned stop-sign red … all before I collapsed in front of a college professor at an academic event.

The blame for my alcohol aversion falls fully on my genetics: Like other people, most of them of East Asian descent, I carry a genetic mutation called ALDH2*2 that causes me to produce broken versions of an enzyme called aldehyde dehydrogenase 2, preventing my body from properly breaking down the toxic components of alcohol. And so, whenever I drink, all sorts of poisons known as aldehydes

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