ARIZONA
he National Park Service wants the public to please refrain from licking toads, specifically the Sonoran Desert (formerly the Colorado River) toad. You might be wondering, “Why is that?” Or, more likely, Turns out that this toad — “one of the largest toads found in North America, measuring up to 7 inches” — has evolved an ingenious defensive feature: a toxic substance secreted from its glands. reports that it contains the “compound 5-MeO-DMT, a